Hi, In case you have undergone transplant then the two most important things to look at are your Renal Function and also What is the cost of medication you are taking. In case your Serum Creation levels are stable at a particular level (obviously within range) the the prognosis is good as perceived by the ircc. You can check the prices of medicines on internet I have a list but somehow not able to insert the link, Also in case you are on Tacrolimus then I guess the patent will be expiring in 2018 or has already expired so the cost of generic med is not much in canada. To put you into perspective I have undergone renal transplant twice, first time in 2006 and second time in 2015, I applied for pr post my second transplant hoping that certainly my case would be rejected on rounds of medical inadmissibility, however there was no rejection and I got it successfully few months back. The annual cost of my medicines in Canada was around $5000/year and the threshold of annual expense for rejecting my application on grounds of excessive demand was I guess around $6655/year. But this limit has been revised to $19,965/year now refer to this news https://www.cicnews.com/2018/04/canada-revises-controversial-medical-inadmissibility-rules-for-immigrants-0410513.html#gs.z3WGiaw However we have to understand that each case is different and it depends on various other factors like Age, qualification, work exp , funds etc. But what I want to say is that do not hold yourself back because of the transplant. You and me we know that life post transplant is as normal and anyone else's or even better since we believe in more health and hygiene than other ;-) So Declare every bit of your relevant medical history to them, be truthful and if they find value in you then u will get it.