My wife and I created an Express Entry profile and were given an Invitation to Apply (Federal Skilled Worker program) last week - we are nearly done with the initial Permanent Residency application forms, but we would like this forum's advice on the question: "Has <applicant> had any serious disease or physical or mental disorder?" - the trouble is, CIC does not provide any insight into what they view as "serious" My wife is the primary applicant, and she has a very mild case of Crohns disease. This was diagnosed almost 5 years ago, and it is well controlled with her medication. She has never required surgery and has no trouble maintaining a full time job - she is not in any way disabled by her condition. However, Crohns can be a serious disease, while in her case it is not, and we are concerned about the implications of answering either "yes" or "no" in the PR application. If we answer "no", we risk appearing as though we are hiding something (which is not our intention). She will be honest during her medical examination, and will have the opportunity to explain her nuanced case to the doctor (I assume?). Basically, while Crohn's can be serious, in her case it is NOT serious (assuming we know what they mean by "serious"), and so can we justify answering "no" to avoid immediately flagging our application off the bat with a potential problem? If we answer "yes", we can enter an explanation in plain text in the form. Either way we risk being labeled as an excessive burden to the Canadian health care system, even though her medical needs for this condition are primarily her medications which the provinces don't cover anyway as we understand. If we do answer "yes", how can we describe the reality of her condition in a way that will help avoid the excessive burden label? Are there other mitigating factors (such as her age - 33 - and the amount of money we are bringing with us - 6 figures) that we can make sure to emphasize? Has anyone had experience with anything like this? Thank you in advance.