The visa denials were for the same basic reasons they usually use for rejecting applications. I’m just worried about it if she will not get approved as i got the medical insurance all the documents. Does not leaving your husband in home country be a strong reason to going back and also work as well
Family ties (like her husband back home) are usually a good reason to get the visa, yes.
But it's impossible to say whether she will be approved or denied. Her past history does count against her because obviously IRCC didn't give her the visa then - I'm assuming she probably had similar family ties on prior applications as well.
However, no point looking for trouble. You have done the best you could, submitted all the right documents and proof. Supervisa applications are different from regular TRV, so you shouldn't worry too much. Wait and see.
The PR status from 11 years ago isn't a bar to getting a supervisa (or any visa).