Hepatitis MAY effect your visa. It's up to them. Coz it requires constant medical attention / supervision / dosage and as Canadian Health care is so expensive, it may rip you apart. BP, Sugar kind of things are of no concerns for VO, but Hepatitis is definitely a concern. They may ask you to wait till you get fully healthy to apply again. But, I heard, they require at least 1 year after your medication is complete and is free from Hepatitis to be considered HEALTHY.