Send a detailed letter to the visa office ( after the application reaches VO) mentioning that the company where you used to work is closed and do give the phone mumbers of your ex managers/ director for reference check, it would be good if you can send any document like notice etc whereby the VO can see the liquidation / closing of your company.
Your getting or not getting a new job, will not effect your application. You can still get the points claimed for the work you had already completed.